Cell biopsy, cell counting, morbid screening of red blood cells, and imaging of cancer biopsies are possible without labeling
In biological and medical research, the detection of cell cultures is fundamental to understanding cell behavior, disease mechanisms, and drug responses. The two-dimensional imaging information provided by traditional biological microscope and fluorescence microscope can not meet the needs of biological and medical scientific research and measurement in the field of cell. Quantitative phase imaging (QPI) can be realized by using the FIS4 wavefront sensor of Jinnekco. Based on the principle of phase detection by common path interferometry, the optical path information in cell and tissue samples can be coupled to the interferogram, and the phase information of the sample can be detected with high precision. Providing accurate phase information enables quantitative analysis of 3D morphology and quality of cells. The FIS4 wavefront interference sensor is a powerful tool for cell culture detection.
The 3D living cell microscope developed based on FIS4 wavefront interference sensor integrates the functions of phase contrast microscope, fluorescence microscope and confocal microscope into one, which can realize cell biopsy, cell count, red blood cell pathological screening and cancer biopsy imaging without labeling. It is a new product for biological and medical research and diagnosis!
Measurement advantage
No reference surface required to avoid impact
High energy pulse beam quality detection
Common channel interference, strong anti-noise ability
On-site, real-time, online detection
Industry application field
▎microscope
▎Cell culture
▎Changes of CELL state at 0 h, 4 h, and 8 h under 20x magnification during CELL AUTOPHAGY of ESC living cells
▎Red blood cell displacement and 3D map at different time
▎Cell automatic recognition and counting function
▎erythrocyte
Monitor the material curing process and optimize print parameters such as speed, flow and light intensity
As the frontier of regenerative medicine, bioprinting technology has become the focus of medical research by using 3D printing to build living tissues and organs that meet the needs of patients. The precision of this technology is essential for the maintenance of cell activity and the integrity of tissue structure, directly affecting the growth and maturation of tissues. The FIS4 wavefront interference sensor monitors print accuracy and interlayer alignment in real time through high-precision interferometry technology, ensuring accuracy at every step. It can detect small print deviations and maintain uniformity and continuity of important structures such as blood vessel walls. In addition, the FIS4 wavefront interference sensor can also monitor the material curing process and optimize printing parameters such as speed, flow and light intensity, thereby improving the overall quality and efficiency of bioprinting. This precise control ensures the advantages of the printed tissue in biological function and structural integrity, which has far-reaching implications for the development and clinical application of bioprinting technology.
Measurement advantage
No reference surface required to avoid impact
High energy pulse beam quality detection
Common channel interference, strong anti-noise ability
On-site, real-time, online detection
Industry application field
▎DNA
▎heart
▎Heart model
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