FIS4-3D living cell microscope
Application: Cancer cell diagnosis, stem cell culture, drug development research, blood morphology observation
◆ LED white light illumination: can maintain the living environment of cells
◆ FIS4 interferometric imaging: high-precision acquisition of three-dimensional morphology and structure of cells
◆ Support bright field imaging: support real-time viewing of cell microstructure in bright field
◆ Different magnification support: Supports observation at 5X, 10X, 20X, 50X, 100X and other magnifications
◆ Electric transfer: An electric two-dimensional stage that supports recording and observation of live organisms in different culture dishes
◆ Electric autofocus: Electric autofocus, supporting multi position autofocus recording
◆ Real time dynamic recording of cells: Recording real-time dynamics of living cells for long-term observation and recording of cellular processes in vivo
◆ Curve generation: supports various analysis curve generation functions
New products for biological and Medical cell culture research and testing: 3D living cell microscopy (marked free 3D real-time imaging) can make up for the shortcomings of phase contrast microscopy, fluorescence microscopy, confocal microscopy in 3D quantitative phase, in vivo, high efficiency and other aspects, realize cell biopsy, cell count, red blood cell pathological screening, cancer living tissue imaging, and provide quantitative analysis of cell contour information 3D morphology and quality!
High contrast
Displays 3D images of cells and various micro and nano fine structures
High efficiency
The detection system is stable and the cell image adjustment is convenient
Living cell detection
Non-staining, non-damaging, long-lasting biopsies of biological cells
Fully functional
With all the viewing functions of a conventional inverted microscope
Ultra high resolution 3D real-time imaging technology, real-time monitoring and tracking of dynamic changes in cells
Accurate cell counting and cell density measurement, real-time monitoring of cellular morphological changes, and output of cell growth curve data
Figure 1: Real time dynamic recording of red blood cell displacement and 3D images at different times by cells
Figure 2: Real time dynamic recording of ESC live cells during CELL AUTOPHAGY process at 20x magnification: changes in cell state at 0 hours, 4 hours, and 8 hours
Example 1: Height values of red blood cells and contour height lines in the AB direction (colors in the image represent different height values)
Example3: E. coli ellipticity, projected area, optical volume, and high point height data
Example3: Stem cell ellipticity, projected area, optical volume, and high point height data
Example4: Stem cell ellipticity, projected area, optical volume, and high point height data
Cell Counting
Application: Counting the number of adherent cells in a culture dish.
Testing: Cell counting and cell density measurement.
Results: Automated cell counting improves experimental efficiency and accuracy, reducing human error.
Cell Quality Control
Application: Quality control to ensure the consistency and stability of cell culture.
Testing: Monitoring the health status of cells and assessing the quality of culture.
Results: Real-time monitoring of cell health status, timely detection of abnormal cells, and ensuring the reliability of experimental results.
Cell Proliferation
Application: Monitoring the rate of cell proliferation.
Testing: Cell proliferation curve, cell division frequency.
Results: Providing data on cell growth curves, assessing the growth status and health level of cells.
Cancer Research
Application: Observing and analyzing the morphology, proliferation, and migration behavior of cancer cells.
Testing: Cancer cell morphological analysis, cell proliferation measure-ment, cell migration path tracking.
Results: Providing high-resolution 3D images, understanding the dynamic changes and migration patterns of cancer cells, promoting the develop-ment of cancer treatment methods.
Drug Discovery and Development
Application: Observing and analyzing the morphology, proliferation, and migration behavior of cancer cells.
Testing: Cancer cell morphological analysis, cell proliferation measurement, cell migration path tracking.
Results: Providing high-resolution 3D images, understanding the dynamic changes and migration patterns of cancer cells, promoting the development of cancer treatment methods.
Stem Cell Research
Application: Study the differentiation process and morphological changes of stem cells.
Testing: Stem cell differentiation, cell morphological change tracking.
Results: Real-time monitoring of stem cell development process, providing detailed information on cell division and differentiation, supporting regenerative medical research.
Wound Healing
Application: Studying cell migration and proliferation during the wound healing process.
Testing: Wound healing speed, cellular repair mechanisms.
Results: Providing dynamic data on cellular repair and regeneration to aid in the development of new therapies for accelerated healing.
Cell Morphology
Application: Observing changes in cell morphology.
Testing: Cell morphology analysis, cell structure observation.
Results: High-resolution images reveal subtle changes in cell morphology, supporting cell biology and morphological research.
Cell Migration
Application: Studying cell migration behavior.
Testing: Analysis of cell migration pathways, migration speed analysis.
Results: Providing data on cell migration trajectories and speeds, understanding mechanisms of cell movement and signal transduction pathways.
Cell Movement and Cell Migration
Application: Observing cell movement and migration processes.
Testing: Cell movement tracking, cell-cell interaction analysis.
Results: Providing real-time data on cell movement, supporting research in tissue repair and regenerative medicine.
Single-cell analysis
Application: Analyzing the behavior and characteristics of individual cells.
Testing: Single-cell morphology, cell behavior analysis.
Results: Providing high-resolution single-cell images and behavioral data to support personalized medicine and precision medical research.
Replaceable multiple magnification microscope objective
This equipment can be optionally equipped with microscope objectives of different magnifications: 5X, 10X, 20X, 50X, 100X; offering unparalleled clarity when observing samples on an ultra-high-definition display
Customizable microscope specific culture dishes, control box heating function, carbon dioxide concentration control
FIS4-MLV live culture dish and control box
FIS4-MLV live culture dish and control box
Intelligent temperature regulation and control, maintaining a constant temperature of 37 ℃
Carbon dioxide concentration control, can be stably maintained at 5%~20%
Reserved multiple air intakes for flexible configuration of special cultivation gas environments
Support multiple types of culture dishes
Flexible, easy to install, and highly versatile
Unrestricted by incubator space, flexible long-term observation of various living cells
Computer requirements
◆ Operating System: Windows 10, 64-bit
◆ Processor: Intel Core i7 (8th Generation)
◆ Memory: 16 GB RAM (minimum 8 GB)
◆ Storage: 512 GB SSD (minimum 256 GB)
◆ Graphics Card: Supports CUDA acceleration, ≥6 GB VRAM
◆ Other: 1 Gigabit Ethernet port
Drug Discovery and Development
◆ Samples and Working Environment
◆ Cells: Monolayer adherent eukaryotic cells
◆ Culture Dish Specifications: 6-, 24-, 96-well, Petri, IBIDI
◆ Operating Temperature: 10-40° C
◆ Operating Humidity: Maximum 95%
By flipping the main body of the microscope and flipping the fixed moving platform, the 3D living cell microscope can be flipped to facilitate the magnification switching and observation in different occasions.
|
Name |
3D living cell microscope |
|
Model |
FIS4-3DCELL |
|
Describe |
3D quantitative phase imaging+2D imaging |
|
Lateral resolution |
1μm（20X） |
|
Phase measurement sensitivity |
2nm |
|
2D imaging pixels |
2048*2048 |
|
3D phase resolution |
512×512 |
|
Focusing method |
electric |
|
Stage |
Electric XY high-precision stage |
|
Objective |
10X (domestic), optional domestic or imported object lens |
◆ Friendly software interface that can automatically generate real-time 3D morphology images of cells
◆ Free selection of cell detection area
◆ Equipped with intelligent cell volume measurement, segmentation, counting and other functions
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