The microstructure and dynamic processes of the tissue were imaged and analyzed

The application of the four-wave transverse shear interferometry (FIS4) technique in biological tissue detection mainly involves imaging and analyzing the microstructure and dynamic processes of tissues. Due to its non-contact and non-invasive characteristics, FIS4 technology is particularly suitable for the study of sensitive biological tissues. Here are some potential applications of the FIS4 technology for biological tissue detection:

1. Tissue surface topography analysis: FIS4 technology can be used to measure the surface roughness and morphological characteristics of biological tissues, which is of great significance for understanding the health state and function of tissues.

2. Imaging internal tissue structure: Through transmission or reflection imaging of tissue samples, FIS4 technology can provide a detailed view of the internal structure of tissues, which can help to identify pathological changes or evaluate the effect of treatment.

3. Cell-matrix interactions: The FIS4 technique can be used to study the interaction of cells with their surrounding matrix, which is crucial for understanding cell behavior in cell migration, wound healing, and tissue engineering.

4. Dynamic biological process monitoring: FIS4 technology can monitor dynamic processes in biological tissues in real time, such as blood flow dynamics, cell migration and tissue deformation, etc., providing important information about physiological and pathological states.

5. Cancer diagnosis and treatment monitoring: FIS4 technology can be used to detect and monitor structural changes in tumor tissue, helping doctors assess the stage of cancer development and treatment response.

6. Nerve tissue research: The structure of nerve tissue is complex and vulnerable to damage, and the non-invasive imaging capability of FIS4 technology makes it a powerful tool for studying neurodegenerative diseases and nerve regeneration.

7. Ophthalmic applications: FIS4 technology can be used for high-resolution imaging of the cornea and retina to help diagnose and monitor eye diseases such as cataracts, glaucoma and macular degeneration.

8. Dermatological research: the surface and internal structure of the skin can be analyzed in detail by FIS4 technology, which is very helpful for early diagnosis and treatment tracking of skin lesions.

Measurement advantage

Complete measurement with a single frame

 

◆ Organize 3D profile measurement

◆ Measurement of tissue size

◆ Support counting, segmentation and weighing

High resolution

 

◆ Up to 512×512 phase sampling points

◆ High dynamic range

◆ Nanoscale sensitivity

Easy to adjust integration

 

◆ Small and compact

◆ Support parallel and convergent beams

◆ Super vibration resistance

Measurement example

Biological tissue detection light path

      

3D Living Cell microscope - Roundworm eggs

Measurement demonstration

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